Causes of meningitis in adults
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Tuberculosis diagnosis by dr najeeb
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A systematic review of cases of meningitis in the absence of cerebrospinal fluid pleocytosis on lumbar puncture
- Research article
- Open access
- Published:
BMC Infectious Diseasesvolume 19, Article number: 692 (2019) Cite this article
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Abstract
Background
Definitive diagnosis of meningitis is made by analysis of cerebrospinal fluid (CSF) culture or polymerase chain reaction (PCR) obtained from a lumbar puncture (LP), which may take days. A timelier diagnostic clue of meningitis is pleocytosis on CSF analysis. However, meningitis may occur in the absence of pleocytosis on CSF.
Areas of Uncertainty: A diagnosis of meningitis seems less likely without pleocytosis on CSF, leading clinicians to prematurely exclude this. Further, there is little available literature on the subject.
Methods
Ovid/Medline and Google Scholar search was conducted for cases of CSF culture-confirmed meningitis with lack of pleocytosis. Inclusion criterion was reported cases of CSF culture-positive or PCR positive meningitis in the absence of
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Muhammad Najeeb Kallidukkil: Personal Informations
Muhammad Najeeb Kallidukkil: Personal Informations
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