Causes of meningitis in adults

Tuberculosis diagnosis by dr najeeb

  • 1. LIAQUAT MEDICAL UNIVERSITY By: DIAGNOSIS OF TUBERCULOSIS Assist: Prof: Faculty of Community Medicine & Public Health Sciences Liaquat University of Medical & Health Sciences (LUMHS) Jamshoro, Sind, Pakistan e mail mnajeeb80@gmail.com
  • 3. Why diagnosis important?  Diagnosis of tuberculosis in most cases  clinical diagnosis based upon the clinical presentation  In 15-20% of p’t with suspected TB  lab confirmation never obtained  Early diagnosis and initiation of effective therapy  reducing morbidity and mortality from TB  minimize the spread of infection
  • 4. Outline  Screening for prior infection  Tuberculin skin test  Diagnosis of pulmonary TB  Medical history  Physical examination  Chest radiograph  Bacteriologic exam
  • 5. Screening for prior infection Tuberculin skin test (little value as a case- finding tool )
  • 6. Screening for prior infection  Whom to screen  Highprevalence and high risk population (HIV)  How to screen  Mantoux tuberculin test (ie, purified protein derivative or PPD, tuberculin skin t

    A systematic review of cases of meningitis in the absence of cerebrospinal fluid pleocytosis on lumbar puncture

    • Research article
    • Open access
    • Published:

    BMC Infectious Diseasesvolume 19, Article number: 692 (2019) Cite this article

    • 11k Accesses

    • 2 Altmetric

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    Abstract

    Background

    Definitive diagnosis of meningitis is made by analysis of cerebrospinal fluid (CSF) culture or polymerase chain reaction (PCR) obtained from a lumbar puncture (LP), which may take days. A timelier diagnostic clue of meningitis is pleocytosis on CSF analysis. However, meningitis may occur in the absence of pleocytosis on CSF.

    Areas of Uncertainty: A diagnosis of meningitis seems less likely without pleocytosis on CSF, leading clinicians to prematurely exclude this. Further, there is little available literature on the subject.

    Methods

    Ovid/Medline and Google Scholar search was conducted for cases of CSF culture-confirmed meningitis with lack of pleocytosis. Inclusion criterion was reported cases of CSF culture-positive or PCR positive meningitis in the absence of

    Muhammad Najeeb Kallidukkil: Personal Informations

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